573 research outputs found
Effective theory for wall-antiwall system
We propose a useful method for deriving the effective theory for a system
where BPS and anti-BPS domain walls coexist. Our method respects an
approximately preserved SUSY near each wall. Due to the finite width of the
walls, SUSY breaking terms arise at tree-level, which are exponentially
suppressed. A practical approximation using the BPS wall solutions is also
discussed. We show that a tachyonic mode appears in the matter sector if the
corresponding mode function has a broader profile than the wall width.Comment: LaTeX file, 30 page, 5 eps figures, references adde
Dirac Equation Studies in the Tunnelling Energy Zone
We investigate the tunnelling zone V0 < E < V0+m for a one-dimensional
potential within the Dirac equation. We find the appearance of superluminal
transit times akin to the Hartman effect.Comment: 12 pages, 4 figure
Entanglement in the quantum Ising model
We study the asymptotic scaling of the entanglement of a block of spins for
the ground state of the one-dimensional quantum Ising model with transverse
field. When the field is sufficiently strong, the entanglement grows at most
logarithmically in the number of spins. The proof utilises a transformation to
a model of classical probability called the continuum random-cluster model, and
is based on a property of the latter model termed ratio weak-mixing. Our proof
applies equally to a large class of disordered interactions
Potential Scattering in Dirac Field Theory
We develop the potential scattering of a spinor within the context of
perturbation field theory. As an application, we reproduce, up to second order
in the potential, the diffusion results for a potential barrier of quantum
mechanics. An immediate consequence is a simple generalization to arbitrary
potential forms, a feature not possible in quantum mechanics.Comment: 7 page
Functional diversity of chemokines and chemokine receptors in response to viral infection of the central nervous system.
Encounters with neurotropic viruses result in varied outcomes ranging from encephalitis, paralytic poliomyelitis or other serious consequences to relatively benign infection. One of the principal factors that control the outcome of infection is the localized tissue response and subsequent immune response directed against the invading toxic agent. It is the role of the immune system to contain and control the spread of virus infection in the central nervous system (CNS), and paradoxically, this response may also be pathologic. Chemokines are potent proinflammatory molecules whose expression within virally infected tissues is often associated with protection and/or pathology which correlates with migration and accumulation of immune cells. Indeed, studies with a neurotropic murine coronavirus, mouse hepatitis virus (MHV), have provided important insight into the functional roles of chemokines and chemokine receptors in participating in various aspects of host defense as well as disease development within the CNS. This chapter will highlight recent discoveries that have provided insight into the diverse biologic roles of chemokines and their receptors in coordinating immune responses following viral infection of the CNS
Traceable measurement and imaging of the complex permittivity of a multiphase mineral specimen at micron scales using a microwave microscope
This paper describes traceable measurements of the dielectric permittivity and loss tangent of a multiphase material (particulate rock set in epoxy) at micron scales using a resonant Near-Field Scanning Microwave Microscope (NSMM) at 1.2 GHz. Calibration and extraction of the permittivity and loss tangent is via an image charge analysis which has been modified by the use of the complex frequency to make it applicable for high loss materials. The results presented are obtained using a spherical probe tip, 0.1 mm in diameter, and also a conical probe tip with a rounded end 0.01 mm in diameter, which allows imaging with higher resolution (≈10 µm). The microscope is calibrated using approach-curve data over a restricted range of gaps (typically between 1% and 10% of tip diameter) as this is found to give the best measurement accuracy. For both tips the uncertainty of scanned measurements of permittivity is estimated to be±10% (at coverage factor k=2) for permittivity ⪝10. Loss tangent can be resolved to approximately 0.001. Subject to this limit, the uncertainty of loss tangent measurements is estimated to be±20% (at k=2). The reported measurements inform studies of how microwave energy interacts with multiphase materials containing microwave absorbent phases
Shorter alkyl chains enhance molecular diffusion and electron transfer kinetics between photosensitisers and catalysts in CO2-reducing photocatalytic liposomes
Covalent functionalisation with alkyl tails is a common method for supporting molecular catalysts and photosensitisers onto lipid bilayers, but the influence of the alkyl chain length on the photocatalytic performances of the resulting liposomes is not well understood. In this work, we first prepared a series of rhenium-based CO2-reduction catalysts [Re(4,4'-(CnH2n+1)(2)-bpy)(CO)(3)Cl] (ReCn; 4,4'-(CnH2n+1)(2)-bpy=4,4'-dialkyl-2,2'-bipyridine) and ruthenium-based photosensitisers [Ru(bpy)(2)(4,4'-(CnH2n+1)(2)-bpy)](PF6)(2) (RuCn) with different alkyl chain lengths (n=0, 9, 12, 15, 17, and 19). We then prepared a series of PEGylated DPPC liposomes containing RuCn and ReCn, hereafter noted C-n, to perform photocatalytic CO2 reduction in the presence of sodium ascorbate. The photocatalytic performance of the C-n liposomes was found to depend on the alkyl tail length, as the turnover number for CO (TON) was inversely correlated to the alkyl chain length, with a more than fivefold higher CO production (TON=14.5) for the C-9 liposomes, compared to C-19 (TON=2.8). Based on immobilisation efficiency quantification, diffusion kinetics, and time-resolved spectroscopy, we identified the main reason for this trend: two types of membrane-bound RuCn species can be found in the membrane, either deeply buried in the bilayer and diffusing slowly, or less buried with much faster diffusion kinetics. Our data suggest that the higher photocatalytic performance of the C-9 system is due to the higher fraction of the more mobile and less buried molecular species, which leads to enhanced electron transfer kinetics between RuC9 and ReC9.Metals in Catalysis, Biomimetics & Inorganic Material
Clinical Pharmacogenetics Implementation Consortium Guideline (CPIC) for CYP2D6 and CYP2C19 Genotypes and Dosing of Tricyclic Antidepressants: 2016 Update
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Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and Tamoxifen Therapy
Personalised Therapeutic
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